Metroid: Other M marks the game soundtrack debut of Kuniaki Haishima, known for composing anime such as Appleseed, Spriggan, and Blue Gender. The soundtrack, particularly the high-quality cutscenes, were recorded by the prestigious Arigat-Orchestra in Tokyo and Asian Philharmonic Orchestra in Beijing.
At first glance, Other M marks a reversal of musical traditions established by Kenji Yamamoto, but on closer inspection, it has more in common with the original Metroid (or the film Aliens) through its use of atmosphere and departure from melody, exemplified in pieces such as “Main Sector”, “Sector 1 (Biosphere) Specimen Observation Area”, and "Sector 3 (Pyrosphere) Industrial Area”. The soundtrack also contains a number of new melodies that fit perfectly with Kenji Yamamoto's scores, including “Sector 1 (Biosphere) Kihunter Hive”, which sounds as if it came directly from Super Metroid; “Green Blood”, “Approaching Sector Zero”, and “Final Mission Resolve”, which all fit with Metroid Fusion's style; the intense battle theme “VS. Mystery Creature"/"VS. Cyborg Zebesians”; the emotional “Piano Medley”; and the inspirational “Staff Roll”. Of course, Other M also sees a return of classic Metroid themes, including the haunting “Title Theme”, “Theme of Super Metroid” in the form of “Load Screen”, "Mysterious Statue Chamber" as "Sector 2 (Cryosphere) Frozen Research Facility", and, of course, the ever-popular “VS. Ridley”.